Apostle technologies have been discussed or cited in the following publications:

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  1. High-resolution DNA size enrichment using a magnetic nano-platform and application in non-invasive prenatal testing. Zhang et al. Analyst. 2020, 145, 5733-5739
  2. Cell-Free DNA Isolation Kit. Science. 17 May 2019:Vol. 364, Issue 6441, pp. 696. DOI: 10.1126/science.364.6441.696-a. (Featured in New Products section)
  3. A complete automation and reagent workflow for analysis of cfDNA: from plasma to variants. Roseman N, Parakh S, Lai K, Sheu J, Wei H, Niccum B, Chen T, Huang H, Barnes T, Lewis L, Chakravarty UD, and Potts A. Advances in Genome Biology and Technology (AGBT). (abstract #511). Marco Island, FL. Feb 23-26, 2020
  4. G3viz: an R package to interactively visualize genetic mutation data using a lollipop-diagram. Xin G, Bo Z, Wenqi Z, et al. Bioinformatics. 2020; 36(3):928–929,
  5. Correlation between mutations found in FFPE tumor tissue and paired cfDNA samples. Niccum B., Heath C., Saunders L., Hur A.,Patel A. Association for Molecular Pathology (AMP). (abstract #ST103). Baltimore, MD. November 7-9, 2019
  6. Dynamics of Plasma EGFR T790M Mutation in Advanced NSCLC: A Multicenter Study. Yang et al. Targeted Oncology. 2019;14:719-728. Published: 06 November 2019.
  7. Correlation between mutations found in FFPE tumor tissue and paired cfDNA samples. (n=8) Niccum B., Saunders L., Hur A.,Patel A. The American Society of Human Genetics (ASHG). (abstract #1766). Houston, TX. Oct 15, 2019
  8. Comparison between mutation profiles of paired whole blood and cfDNA samples. Patel A., Saunders L., Hur A. The American Society of Human Genetics (ASHG). (abstract #1767). Houston, TX. Oct 15, 2019
  9. Isolation of cell-free DNA (cfDNA) from plasma using Apostle MiniMaxTM High Efficiency cfDNA Isolation kit—comparison of fully automated, semi-automated and manual workflow processing. Brittany Niccum, PhD., Randy Pares and Antonia Hur. Beckman Coulter Life Sciences. Application Note. Sept 2019.
  10. A workflow for medium-throughput isolation of cfDNA from plasma samples using Apostle MiniMaxTM on the KingFisherTM Technology. Brittany Niccum, PhD. Beckman Coulter Life Sciences. Application Note. 2019.
  11. Correlation between mutations found in FFPE tumor tissue and paired cfDNA samples. (n=3) Saunders L and Patel A. American Association for Cancer Research (AACR). (abstract #2233). Atlanta, GA. April 2, 2019
  12. A new Scalable and automatable method for the extration of cfDNA. Saunders LP, Hur A, Niccum B, and Patel A. Advances in Genome Biology and Technology (AGBT). (abstract #419). Marco Island, FL. Feb 28, 2019
  13. cfDNA Extraction from Plasma for Liquid Biopsy: Apostle MiniMaxTM High Efficiency cfDNA Isolation Kit. Beckman Coulter Life Sciences, Data Sheet. 2019.

A list of Documentation provided by Beckman Coulter Life Sciences:

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Team's track record of publications

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D. Ge

  1. Ge D*, Fellay J*, Thompson AJ*, Simon JS*, Shianna KV, Urban TJ, Heinzen EL, Qiu P, Bertelsen AH, Muir AJ, Sulkowski M, McHutchison JG, Goldstein DB. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 2009:461, 399-401.
    • Featured in Nature: news & views: Genomics: Hepatitis C virus gets personal. Nature 2009; 461 (357-358).
    Nature: Outlook: Pharmacogenomics: playing the odds. Nature. 2011;474(7350):S9-10.
    • Licensed to: LabCorp Inc.; Quest Diagnostics Inc.
    • Citations: 3900+
    • Ranked No. 7 across all scientific areas published by Nature (Google Scholar Metrics, 2015)
  2. Fellay J*, Thompson AJ*, Ge D*, Gumbs CE, Urban TJ, Shianna KV, et al. ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. Nature. 2010;464(7287):405-8. (* Equal co-authors)
  3. Thomas DL, Thio CL, Martin MP, Qi Y, Ge D, O'hUigin C, Kidd J, Kidd K, Khakoo SI, Alexander G, Goedert JJ, Kirk GD, Donfield SM, Rosen HR, Tobler LH, Busch MP, McHutchison JG, Goldstein DB, Carrington M. Genetic variation in IL28B and spontaneous clearance of hepatitis C virus. Nature 2009; 461, 798-801.
  4. Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietilainen OP, Mors O, Mortensen PB, Sigurdsson E, Gustafsson O, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Suvisaari J, Lonnqvist J, Paunio T, Borglum AD, Hartmann A, Fink-Jensen A, Nordentoft M, Hougaard D, Norgaard-Pedersen B, Bottcher Y, Olesen J, Breuer R, Moller HJ, Giegling I, Rasmussen HB, Timm S, Mattheisen M, Bitter I, Rethelyi JM, Magnusdottir BB, Sigmundsson T, Olason P, Masson G, Gulcher JR, Haraldsson M, Fossdal R, Thorgeirsson TE, Thorsteinsdottir U, Ruggeri M, Tosato S, Franke B, Strengman E, Kiemeney LA, Group, Melle I, Djurovic S, Abramova L, Kaleda V, Sanjuan J, de Frutos R, Bramon E, Vassos E, Fraser G, Ettinger U, Picchioni M, Walker N, Toulopoulou T, Need AC, Ge D, Lim Yoon J, Shianna KV, Freimer NB, Cantor RM, Murray R, Kong A, Golimbet V, Carracedo A, Arango C, Costas J, Jonsson EG, Terenius L, Agartz I, Petursson H, Nothen MM, Rietschel M, Matthews PM, Muglia P, Peltonen L, St Clair D, Goldstein DB, Stefansson K, Collier DA, Kahn RS, Linszen DH, van Os J, Wiersma D, Bruggeman R, Cahn W, de Haan L, Krabbendam L, Myin-Germeys I. Common variants conferring risk of schizophrenia. Nature 2009:460(7256):744-7
  5. Stefansson H, Rujescu D, Cichon S, Pietilainen OP, Ingason A, Steinberg S, Fossdal R, Sigurdsson E, Sigmundsson T, Buizer-Voskamp JE, Hansen T, Jakobsen KD, Muglia P, Francks C, Matthews PM, Gylfason A, Halldorsson BV, Gudbjartsson D, Thorgeirsson TE, Sigurdsson A, Jonasdottir A, Jonasdottir A, Bjornsson A, Mattiasdottir S, Blondal T, Haraldsson M, Magnusdottir BB, Giegling I, Moller HJ, Hartmann A, Shianna KV, Ge D , Need AC, Crombie C, Fraser G, Walker N, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Paunio T, Toulopoulou T, Bramon E, Di Forti M, Murray R, Ruggeri M, Vassos E, Tosato S, Walshe M, Li T, Vasilescu C, Muhleisen TW, Wang AG, Ullum H, Djurovic S, Melle I, Olesen J, Kiemeney LA, Franke B, Kahn RS, Linszen D, van Os J, Wiersma D, Bruggeman R, Cahn W, Germeys I, de Haan L, Krabbendam L, Sabatti C, Freimer NB, Gulcher JR, Thorsteinsdottir U, Kong A, Andreassen OA, Ophoff RA, Georgi A, Rietschel M, Werge T, Petursson H, Goldstein DB, Nothen MM, Peltonen L, Collier DA, St Clair D, Stefansson K. Large recurrent microdeletions associated with schizophrenia. Nature . 2008;455(7210):232-6.
  6. Fellay J, Shianna KV *, Ge D *, Colombo S *, Ledergerber B *, Weale M *, Zhang K, Gumbs C, Castagna A, Cossarizza A, Cozzi-Lepri A, De Luca A, Easterbrook P, Francioli P, Mallal S, Martinez-Picado J, Miro JM, Obel N, Smith JP, Wyniger J, Descombes P, Antonarakis SE, Letvin NL, McMichael AJ, Haynes BF, Telenti A, Goldstein DB. A whole-genome association study of major determinants for host control of HIV-1. Science . 2007;317(5840):944-7. (* Equal authors) (Citations: 390)
  7. Thomas R, Apps R, Qi Y, Gao X, Male V, O'HUigin C, O'Connor G, Ge D, et al. HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C. Nat Genet. 2009;41(12):1290-4.
  8. Ge D, Ruzzo EK, Shianna KV, He M, Pelak K, Heinzen EL, Need AC, Cirulli ET, Maia JM, Zhu M, Singh A, Allen AS, Goldstein DB. SVA: Software for Annotating and Visualizing Sequenced Human Genomes. Bioinformatics, 2011;27(14):1998-2000. (software: )
  9. Zhu Q *, Ge D*, Maia JM, Zhu M, Petrovski S, Dickson SP, Heinzen EL, Shianna KV, Goldstein DB. A Genome-Wide Comparison of the Functional Properties of Rare and Common Genetic Variants in Humans. American Journal of Human Genetics. 2011;88(4):458-68.
  10. W. J. Sandborn, B. R. Bhandari, R. Fogel, J. Onken, E. Yen, X. Zhao, Z. Jiang, D. Ge, Y. Xin, Z. Ye, D. French, J. A. Silverman, B. Kanwar, G. M. Subramanian, J. G. McHutchison, S. D. Lee, L. M. Shackelton, R. K. Pai, B. G. Levesque & B. G. Feagan. Randomised clinical trial: a phase 1, dose-ranging study of the anti-matrix metalloproteinase-9 monoclonal antibody GS-5745 versus placebo for ulcerative colitis. Alimentary Pharmacology and Therapeutics. 2016 (In press)
  11. Charuworn P, Hengen PN, Aguilar Schall R, Dinh P, Ge D, Corsa A, Reesink HW, Zoulim F, Kitrinos KM. Baseline interpatient hepatitis B viral diversity differentiates HBsAg outcomes in patients treated with tenofovir disoproxil fumarate. J Hepatol. 2015 May;62(5):1033-9.
  12. Nelson D, Yoshida EM, Paulson MS, Hengen MS, Hengen PN, Ge D, Kanwar B, McNally J, Pang PS, Subramanian GM, McHutchison JG, Urbanek P, Lawitz E, Urban TJ. Genome-wide association study to characterize serum bilirubin elevations in patients with HCV treated with GS-9256, an HCV NS3 serine protease inhibitor. Antiviral Therapy. 2014 Feb 6. doi: 10.3851/IMP2747.
  13. Pelak K*, Shianna KV*, Ge D*, Maia JM, Zhu M, Smith JP, et al. The characterization of twenty sequenced human genomes. PLoS Genet. 2010;6(9): e1001111.
  14. Sobreira NLM, Cirulli ET, Avramopoulos D, Wohler E, Oswald GL, Stevens EL, Ge D, et al. Whole-Genome Sequencing of a Single Proband Together with Linkage Analysis Identifies a Mendelian Disease Gene. PLoS Genet 2010;6(6):e1000991.
  15. Todd J, Goldstein DB, Ge D, Christie J, Palmer, SM. The State of Genome-Wide Association Studies in Pulmonary Disease: A New Perspective. American Journal of Respiratory and Critical Care Medicine. 2011.
  16. Thompson AJ, Muir AJ, Sulkowski MS, Patel K, Tillmann HL, Clark PJ, Naggie S, Fellay J, Ge D, McCarthy JJ et al: Hepatitis C trials that combine investigational agents with pegylated interferon should be stratified by interleukin-28B genotype. Hepatology 2010, 52(6):2243-2244.
  17. Thompson AJ, Clark PJ, Singh A, Ge D, et al. Genome-wide association study of interferon-related cytopenia in chronic hepatitis C patients. J Hepatol. 2011.
  18. Thompson AJ, Fellay J, Patel K, Tillmann HL, Naggie S, Ge D, et al. Variants in the ITPA Gene Protect Against Ribavirin-Induced Hemolytic Anemia and Decrease the Need for Ribavirin Dose Reduction. Gastroenterology. 2010;139(4):1181-9.
  19. Thompson AJ, Muir AJ, Sulkowski MS, Ge D, et al. Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus. Gastroenterology. 2010;139(1):120-9 e18.
  20. Walley NM, Julg B, Dickson SP, Fellay J, Ge D, Walker BD, Carrington M, Cohen MS, de Bakker PI, Goldstein DB, Shianna KV, Haynes BF, Letvin NL, McMichael AJ, Michael NL, Weintrob AC. The Duffy antigen receptor for chemokines null promoter variant does not influence HIV-1 acquisition or disease progression. Cell Host Microbe 2009; 5 (5) : 408-10.
  21. Need AC, Attix DK, McEvoy JM, Cirulli ET, Linney KL, Hunt P, Ge D, Heinzen EL, Maia JM, Shianna KV, Weale ME, Cherkas LF, Clement G, Spector TD, Gibson G, Goldstein DB. A Genome-wide Study of Common SNPs and CNVs in Cognitive Performance in the CANTAB battery. Hum Mol Genet 2009.
  22. Pillai SG, Ge D *, Zhu G*, Kong X*, Shianna KV, Need AC, S. F, Hersh CP, Bakkgators, Rennard SI, Lomas D, Silverman EK, Goldstein DB. A Genome-wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of two Major Susceptibility Loci. PLoS Genet . 2009; 5(3): e1000421. doi:10.1371/journal.pgen.1000421 (* Equal authors)
  23. Need AC *, Ge D * , Maia J, Shianna KV, Feng S, Strittmatter WJ, McEvoy JP, Keefe RSE, St Jean PL, Giegling I, Hartmann AM, M?ller H, Ruppert A, Fraser G, Crombie C, Francks C, St.Clair D, Roses AD, Muglia P, Rujescu D, Goldstein DB. A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia. PLoS Genet. 2009; 5(2):e1000373.(* Equal authors)
  24. Heinzen E *, Ge D *, Cronin KD, Maia J, Shianna KV, Gabriel W, Welsh-Bohmer KA, Hulette CM, Denny T, Goldstein DB. Tissue specific genetic control of gene expression and alternative splicing: Implications for the study of human complex traits. PLoS Biol . 2008; 6(12): e1000001. (* Equal authors)
  25. Ge D , Zhang K, Need AC, Martin O, Fellay J, Urban TJ, Telenti A, Goldstein DB. WGAViewer: Software for genomic annotation of whole genome association studies. Genome Research. 2008;18(4):640-3. (citations: 87)
  26. Price AL, Weale ME, Patterson N, Myers SR, Need AC, Shianna KV, Ge D , Rotter JI, Torres E, Taylor KD, Goldstein DB, Reich D. Long-range LD can confound genome scans in admixed populations. Am J Hum Genet 2008 . 83(1):132-5.
  27. Cavalleri GL, Weale ME, Shianna KV, Singh R, Lynch JM, Grinton B, Szoeke C, Murphy K, Kinirons P, O'Rourke D, Ge D , Depondt C, Claeys KG, Pandolfo M, Gumbs C, Walley N, McNamara J, Mulley JC, Linney KN, Sheffield LJ, Radtke RA, Tate SK, Chissoe SL, Gibson RA, Hosford D, Stanton A, Graves TD, Hanna MG, Eriksson K, Kantanen AM, Kalviainen R, O'Brien TJ, Sander JW, Duncan JS, Scheffer IE, Berkovic SF, Wood NW, Doherty CP, Delanty N, Sisodiya SM, Goldstein DB. Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case-control study. Lancet Neurol. 2007;6(11):970-80.
  28. Valdes AM, Loughlin J, Timms KM, van Meurs JJ, Southam L, Wilson SG, Doherty S, Lories RJ, Luyten FP, Gutin A, Abkevich V, Ge D, Hofman A, Uitterlinden AG, Hart DJ, Zhang F, Zhai G, Egli RJ, Doherty M, Lanchbury J, Spector TD. Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis. Am J Hum Genet 2008;82(6):1231-40.
  29. Cronin KD, Ge D, Manninger P, Linnertz C, Rossoshek A, Orrison BM, Bernard DJ, El-Agnaf OM, Schlossmacher MG, Nussbaum RL, Chiba-Falek O. Expansion of the Parkinson Disease-Associated SNCA-Rep1 Allele Up-Regulates Human {alpha}-Synuclein in Transgenic Mouse Brain. Hum Mol Genet 2009.
  30. Need AC, Keefe RS, Ge D, Grossman I, Dickson S, McEvoy JP, Goldstein DB. Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. Eur J Hum Genet 2009; 17 (7) : 946-57 .
  31. Ge D , Su S, Zhu H, Dong Y, Wang X, Harshfield GA, Treiber FA, Snieder H. Stress-Induced Sodium Excretion. A New Intermediate Phenotype to Study the Early Genetic Etiology of Hypertension? Hypertension 2009;53:262-269
  32. Ge D , Gooljar SB, Kyriakou T, Collins LJ, Swaminathan R, Snieder H, Spector TD, O'Dell SD. Association of Common JAK2 Variants With Body Fat, Insulin Sensitivity and Lipid Profile. Obesity (Silver Spring) 2008;16(2) : 492-6.
  33. Ge D, Zhu H, Huang Y, Treiber FA, Harshfield GA, Snieder H, Dong Y. Multilocus analyses of Renin-Angiotensin-aldosterone system gene variants on blood pressure at rest and during behavioral stress in young normotensive subjects. Hypertension . 2007 ;49(1):107-12.
  34. Ge D, Young TW, Wang X, Kapuku GK, Treiber FA, Snieder H. Heritability of arterial stiffness in black and white American youth and young adults. Am J Hypertens 2007;20(10) : 1065-72.
  35. Kapuku GK, Ge D, Vemulapalli S, Harshfield GA, Treiber FA, Snieder H. Change of genetic determinants of left ventricular structure in adolescence: longitudinal evidence from the Georgia cardiovascular twin study. Am J Hypertens 2008;21(7):799-805.
  36. Oberg S, Ge D, Cnattingius S, Svensson A, Treiber FA, Snieder H, Iliadou A. Ethnic differences in the association of birth weight and blood pressure the georgia cardiovascular twin study. Am J Hypertens 2007;20(12):1235-41.
  37. Zhu H, Yan W, Ge D , Treiber FA, Harshfield GA, Kapuku G, Snieder H, Dong Y. Relationships of cardiovascular phenotypes with healthy weight, at risk of overweight, and overweight in US youths. Pediatrics 2008;121(1) : 115-22.
  38. Wang L, Li B, Lu X, Zhao Q, Li Y, Ge D, Li H, Zhang P, Chen S, Chen R, Qiang B, Gu D. A functional intronic variant in tyrosine hydroxylase (TH) gene confers risk of essential hypertension in northern Chinese Han population. Clin Sci (Lond) 2008.
  39. Dalageorgou C, Ge D , Jamshidi Y, Nolte IM, Riese H, Savelieva I, Carter ND, Spector TD, Snieder H. Heritability of QT Interval: How Much Is Explained by Genes for Resting Heart Rate? J Cardiovasc Electrophysiol 2007.
  40. Morell RJ, Brewer CC, Ge D , Snieder H, Zalewski CK, King KA, Drayna D, Friedman TB. A twin study of auditory processing indicates that dichotic listening ability is a strongly heritable trait. Hum Genet 2007;122(1):103-11.
  41. Zhu H, Yan W, Ge D, Treiber FA, Harshfield GA, Kapuku G, Snieder H, Dong Y. Cardiovascular characteristics in American youth with prehypertension. Am J Hypertens 2007;20(10):1051-7.
  42. Jamshidi Y, Snieder H, Ge D , Spector TD, O'Dell SD. The SH2B gene is associated with serum leptin and body fat in normal female twins. Obesity (Silver Spring) . 2007;15(1):5-9.
  43. Healey PR, Mitchell P, Gilbert CE, Lee AJ, Ge D , Snieder H, Spector TD, Hammond CJ. The inheritance of peripapillary atrophy. Invest Ophthalmol Vis Sci 2007;48(6):2529-34.
  44. Weili Y, He B, Yao H, Dai J, Cui J, Ge D , Zheng Y, Li L, Guo Y, Xiao K, Fu X, Ma D. Waist-to-height ratio is an accurate and easier index for evaluating obesity in children and adolescents. Obesity (Silver Spring) 2007;15(3):748-52.
  45. Jamshidi Y, Gooljar SB, Snieder H, Wang X, Ge D , Swaminathan R, Spector TD, O'Dell SD. SHP-2 and PI3-kinase genes PTPN11 and PIK3R1 may influence serum apoB and LDL cholesterol levels in normal women. Atherosclerosis 2007; 194 (2) : e26-33
  46. Ge D, Dong Y, Wang X, Treiber FA, Snieder H. The Georgia Cardiovascular Twin Study: influence of genetic predisposition and chronic stress on risk for cardiovascular disease and type 2 diabetes. Twin Res Hum Genet . 2006;9(6):965-70.
  47. Spencer-Jones NJ*, Ge D *, Snieder H, Perks U, Swaminathan R, Spector TD, Carter ND, O'Dell SD. AMP-kinase alpha2 subunit gene PRKAA2 variants are associated with total cholesterol, low-density lipoprotein-cholesterol and high-density lipoprotein-cholesterol in normal women. Journal of Medical Genetics. 2006 ;43(12):936-42. (* Joint authors.)
  48. Gu D, Ge D, Snieder H, He J, Chen S, Huang J, Li B, Chen R, Qiang B. Association of alpha-1A adrenergic receptor gene variants on chromosome 8p21 with human stage-2 hypertension. Journal of Hypertension , 2006;24(6):1057-1064.
  49. Kupper N, Ge D, Treiber FA, Snieder H . Tracking of blood pressure and underlying hemodynamics in European and African American adolescents. Stable heritabilities and expression of new genes. Hypertension , 2006 47(5):948-54 .
  50. Gu D, Su S, Ge D, Chen S, Huang J, Li B, Chen R, Qiang B. An Association Study with 33 SNPs in 11 Candidate Genes for Hypertension in Chinese. Hypertension , 2006;47(6):1147-54.
  51. Herold SE, Young TW, Ge D, Snieder H, Lovrekovic GZ. Sleep Disordered Breathing in Pediatric Patients with Tetralogy of Fallot. Pediatric Cardiology , 2006;27(2):243-9.
  52. de Lange M, Andrew T, Snieder H, Ge D, Futers TS, Standeven K, Spector TD, Grant PJ and Ariens RAS. Joint linkage and association of 6 single nucleotide polymorphisms in the factor XIII-A subunit gene point to V34L as the main functional locus. Arteriosclerosis, Thrombosis, and Vascular Biology . 2006 Aug;26(8):1914-9.
  53. Yang W, Huang J, Yao C, Su S, Liu D, Ge D , Gu D. Linkage and linkage disequilibrium analysis of the lipoprotein lipase gene with lipid profiles in Chinese hypertensive families. Clinical Science (Lond). 2005;108(2):137-142.
  54. Ge D, Huang J, Yang W, Zhao J, Shen Y, Qiang B, Gu D. Linkage analysis of chromosome 1 with essential hypertension and blood pressure quantitative traits in Chinese families. Annals of Human Genetics . 2005;69(Pt 1):45-54.
  55. Ge D , Huang J, He J, Li B, Duan X, Chen R, Gu D. beta2-Adrenergic receptor gene variations associated with stage-2 hypertension in northern Han Chinese. Annals of Human Genetics . 2005;69(Pt 1):36-44.
  56. Li B, Ge D , Wang Y, Zhao W, Zhou X, Gu D, Chen R. G Protein beta3 Subunit Gene Variants and Essential Hypertension in the Northern Chinese Han Population. Annals of Human Genetics . 2005;69(Pt 4):468-473.
  57. Chen S, Yan W, Huang J, Ge D, Yao Z, Gu D. Association analysis of the variant in the regulatory subunit of phosphoinositide 3-kinase (p85alpha) with Type 2 diabetes mellitus and hypertension in the Chinese Han population. Diabetic Medicine . 2005;22(6):737-743.
  58. Yan W, Yang X, Zheng Y, Ge D , Zhang Y, Shan Z , Simu H , Sukerobai M , Wang R . The Metabolic Syndrome in Uygur and Kazak Population. Diabetes Care . 28(10):2554-5, 2005.
  59. Zhou X, Huang J, Chen J, Zhao J, Ge D , Yang W, Gu D. Genetic association analysis of myocardial infarction with thrombospondin-1 N700S variant in a Chinese population. Thrombosis Research . 2004;113(3-4):181-186.
  60. Gu D, Ge D, He J, Li B, Chen J, Liu D, Chen J, Chen R. Haplotypic analyses of the aldosterone synthase gene CYP11B2 associated with stage-2 hypertension in northern Han Chinese. Clinical Genetics . 2004;66(5):409-416.
  61. Li B, Ge D, Wang Y, Zhao W, Zhou X, Gu D, Chen R. Lipoprotein lipase gene polymorphisms and blood pressure levels in the Northern Chinese Han population. Hypertension Research . 2004;27(6):373-378.
  62. Gu F, Ge D, Huang J, Chen J, Yang W, Gu D. Genetic susceptibility loci for essential hypertension and blood pressure on chromosome 17 in 147 Chinese pedigrees. Journal of Hypertension . 2004;22(8):1511-1518.
  63. Gu D, Ge D. The New Genetics in Hypertension: Asia Pacific Perspective. Paper presented at: 3rd Asian-Pacific Congress of Hypertension; April 3-7, 2004; Singapore.

B. Zhang

  1. Bo Zhang (1st and Corresponding author), Benjamin A. Pinsky, Jeyarama S. Ananta, Su Zhao, Shylaja Arulkumar, Hao Wan, Malaya K. Sahoo, Janaki Abeynayake, Jesse J. Waggoner, Clay Hopes, Meijie Tang and Hongjie Dai. “Diagnosis of Zika virus infection on a nanotechnology platform” Nature Medicine, 23, 548, 2017.
  2. Christelle Pomares, Bo Zhang (co-1st and Corresponding author), Shylaja Arulkumar, Geraldine Gonfrier, Pierre Marty, Su Zhao, Steven Cheng, Meijie Tang, Hongjie Dai and Jose Montoya. “Validation of IgG, IgM multiplex plasmonic gold platform in French clinical cohorts for the serodiagnosis and follow up of Toxoplasma gondii infection” Diagnostic Microbiology & Infectious Disease, 87, 213, 2017.
  3. Xiaohua Chen, Odgerel Oidovsambuu, Ping Liu, Rosslyn Grosely, Menashe Elazar, Virginia D Winn, Benjamin Fram, Zhang Bo, Hongjie Dai, Bekhbold Dashtseren, Dahgwahdorj Yagaanbuyant, Zulkhuu Genden, Naranbaatar Dashdorj, Andreas Bungert, Naranjargal Dashdorj, Jeffrey S Glenn. “A novel quantitative microarray antibody capture (Q‐MAC) assay identifies an extremely high HDV prevalence amongst HBV infected Mongolians” Hepatology, DOI: 10.1002/hep.28957, 2016.
  4. Shoujun Zhu, Qinglai Yang, Alexander Antaris, Jingying Yue, Zhuoran Ma, Huasen Wang, Wei Huang, Hao Wan, Joy Wang, Shuo Diao, Bo Zhang, Xiaoyang Li, Yeteng Zhong, Kuai Yu, Guosong Hong, Jian Luo, Yongye Liang and Hongjie Dai. “Molecular imaging of biological systems with a clickable dye in the broad 800- to 1700-nm near-infrared window” Proceedings of the National Academy of Sciences, 114, 962, 2016.
  5. Bin Liu, Yaling Li, Hao Wan, Lin Wang, Wei Xu, Shoujun Zhu, Yongye Liang, Bo Zhang, Jiatao Lou, Hongjie Dai and Kun Qian. “High performance, multiplexed lung cancer biomarker detection on a plasmonic gold chip” Advanced Functional Materials, 26, 7994, 2016.
  6. Byumseok Koh, Xiaoyang Li, Bo Zhang, Bing Yuan, Yi Lin, Alexander L. Antaris, Hao Wan, Ming Gong, Jiang Yang, Xiaodong Zhang, Yongye Liang, and Dai. "Visible to Near-Infrared Fluorescence Enhanced Cellular Imaging on Plasmonic Gold Chips" Small, 12, 457, 2016.
  7. Alexander L Antaris, Hao Chen, Kai Cheng, Yao Sun, Guosong Hong, Chunrong Qu, Shuo Diao, Zixin Deng, Xianming Hu, Bo Zhang, Xiaodong Zhang, Omar K Yaghi, Zita R Alamparambil, Xuechuan Hong, Zhen Cheng and Hongjie Dai. “A small-molecule dye for NIR-II imaging” Nature materials, 15, 235, 2016.
  8. Shuo Diao, Jeffrey L Blackburn, Guosong Hong, Alexander L Antaris, Junlei Chang, Justin Z Wu, Bo Zhang, Kai Cheng, Calvin J Kuo and Hongjie Dai. “Fluorescence Imaging In Vivo at Wavelengths beyond 1500 nm” Angewandte Chemie, 127, 14971, 2015.
  9. Valentina Manfe, Jan Fleckner, Peder Norby Lisby, Bo Zhang, Hongjie Dai and Pernille Keller. “Cytokine detection and simultaneous assessment of rheumatoid factor interference in human serum and synovial fluid using high-sensitivity protein arrays on plasmonic gold chips” BMC Biotechnology, 15, 73, 2015.
  10. Changxin Chen, Justin Zachary Wu, Kai Tak Lam, Guosong Hong, Ming Gong, Bo Zhang, Yang Lu, Alexander L. Antaris, Shuo Diao, Jing Guo, and Hongjie Dai. "Graphene Nanoribbons Under Mechanical Strain" Advanced Materials, 27, 303-309, 2015.
  11. Alexander L. Antaris, Omar K. Yaghi, Guosong Hong, Shuo Diao, Bo Zhang, Jiang Yang, Leila Chew, and Hongjie Dai. “Single chirality (6,4) single-walled carbon nanotubes for fluorescence imaging with silicon detectors” Small, 11, 6325-6330, 2015.
  12. Bo Zhang, Rajiv Kumar, Hongjie Dai and Brian Feldman. “A plasmonic Chip for Biomarker Discovery and Diagnosis of Type-1 Diabetes.” Nature Medicine, 20, 948, 2014.
  13. Bo Zhang, Jiang Yang, Yingping Zou, Ming Gong, Hui Chen, Guosong Hong, Alexander L. Antaris, Xiaoyang Li, Chien-Liang Liu, Changxin Chen and Hongjie Dai. “Plasmonic micro-beads for fluorescence enhanced, multiplexed protein detection with flow cytometry.” Chemical Science, 5, 4070, 2014.
  14. Brian Feldman, Rajiv Kumar, Bo Zhang, and Hongjie Dai. “A novel plasmonic chip for biomarker discovery and point-of-care diagnosis of Type-1 Diabetes.” Endocrine Reviews, 35, 3, 2014.
  15. Guosong Hong, Shuo Diao, Junlei Chang, Alexander L. Antaris, Changxin Chen, Bo Zhang, Su Zhao, Dmitriy N. Atochin, Paul L. Huang, Katrin I. Andreasson, Calvin J. Kuo, and Hongjie Dai. “Through-skull fluorescence imaging of the brain in a new near-infrared window.” Nature Photonics, 8, 723, 2014.
  16. Ming Gong, Wu Zhou, Mon-Che Tsai, Jigang Zhou, Mingyun Guan, Meng-Chang Lin, Bo Zhang, Yongfeng Hu, Di-Yan Wang, Jiang Yang, Stephen J. Pennycook, Bing-Joe Hwang and Hongjie Dai. “Nanoscale nickel oxide/nickel heterostructures for active hydrogen evolution electrocatalysis.” Nature Communications, 5, 4695, 2014.
  17. Guosong Hong, Yingping Zou, Alexander L. Antaris, Shuo Diao, Di Wu, Kai Cheng, Xiaodong Zhang, Changxin Chen, Bo Liu, Yuehui He, Justin Z. Wu, Jun Yuan, Bo Zhang, Zhimin Tao, Chihiro Fukunaga and Hongjie Dai. “Ultrafast fluorescence imaging in vivo with conjugated polymer fluorophores in the second near-infrared window.” Nature Communications, 5, 4206, 2014.
  18. Xiaobin Tang, Bo Zhang, Justin A. Jarrell, Jordan V. Price, Hongjie Dai, Paul J Utz and Sam Strober. “Ly108 expression distinguishes subsets of invariant NKT cells that help autoantibody production and secrete IL-21 from those that secrete IL-17 in lupus prone NZB/W mice.” Journal of Autoimmunity, 50, 87, 2014.
  19. Ming Gong, Yanguang Li, Hongbo Zhang, Bo Zhang, Wu Zhou, Ju Feng, Hailiang Wang, Yongye Liang, Zhuangjun Fan, Jie Liu and Hongjie Dai. “Ultrafast high-capacity NiZn battery with NiAlCo-layered double hydroxide.” Energy and Environmental Science, 7, 2025, 2014.
  20. Zhimin Tao, Guosong Hong, Chihiro Shinji, Changxin Chen, Shuo Diao, Alexander L. Antaris, Bo Zhang, Yingping Zou and Hongjie Dai. “Biological imaging using nanoparticles of small organic molecules with fluorescence at wavelengths longer than 1000 nm.” Angewante Chemie, 125 (49), 13240, 2013.
  21. Bo Zhang, Justin A. Jarrell, Jordan V. Price, Scott M. Tabakman, Yanguang Li, Ming, Gong, Guosong Hong, Ju Feng, Paul J. Utz and Hongjie Dai. “An integrated peptide-antigen microarray on plasmonic gold films for sensitive human antibody profiling.” Plos ONE, 8, e71043, 2013.
  22. Yanguang Li, Ming Gong, Yongye Liang, Ju Feng, Ji-Eun Kim, Hailiang Wang, Guosong Hong, Bo Zhang and Hongjie Dai. “Advanced zinc-air batteries based on high-performance hybrid electrocatalysts.” Nature Communications, 4, 1805, 2013.
  23. Bo Zhang, Jordan Price, Guosong Hong, Scott M. Tabakman, Hailiang Wang, Justin A. Jarrell, Ju Feng, Paul J. Utz and Hongjie Dai. “Multiplexed cytokine detection on plasmonic gold substrates with enhanced near-infrared fluorescence.” Nano Research, 6, 113, 2013.
  24. Ju Feng, Yongye Liang, Hailiang Wang, Yanguang Li, Bo Zhang, Jigang Zhou, Jian Wang, Tom Regier and Hongjie Dai. “Engineering manganese oxide/nanocarbon hybrid materials for oxygen reduction electrocatalysis.” Nano Research, 5 (10), 718, 2012.
  25. Joshua T. Robinson, Guosong Hong, Yongye Liang, Bo Zhang, Omar K. Yaghi and Hongjie Dai. “In vivo fluorescence imaging in the second near-infrared window with long circulating carbon nanotubes capable of ultrahigh tumor uptake.” Journal of the American Chemical Society, 134 (25), 10664, 2012.
  26. Guosong Hong, Justin Z. Wu, Joshua T. Robinson, Hailiang Wang, Bo Zhang and Hongjie Dai. “Three-dimensional imaging of single nanotube molecule endocytosis on plasmonic substrates.” Nature Communications, 3, 700, 2012.
  27. Scott M. Tabakman, Lana Lau, Joshua T. Robinson, Jordan Price, Sarah P. Sherlock, Hailiang Wang, Bo Zhang, Zhuo Chen, Stephanie Tangsombatvisit, Justin A. Jarrell, Paul J. Utz and Hongjie Dai. “Plasmonic substrates for multiplexed protein microarrays with femtomolar sensitivity and broad dynamic range.” Nature Communications, 2, 466, 2011.
  28. Guosong Hong, Scott M. Tabakman, Kevin Welsher, Zhuo Chen, Joshua T. Robinson, Hailiang Wang, Bo Zhang and Hongjie Dai. “Near-infrared-fluorescence-enhanced molecular imaging of live cells on gold substrates.” Angewante Chemie, 50, 4644, 2011.
  29. Guo Hong, Bo Zhang, Banghua Peng, Xiaojun Xian, Jin Zhang, WonMook Choi, Jae-Young Choi, Jong Min Kim and Zhongfan Liu. “Direct growth of semiconducting single-walled carbon nanotube array.” Journal of the American Chemical Society, 131, 14642, 2009.
  30. Bo Zhang, Guo Hong, Banghua Peng, Jin Zhang, WonMook Choi, Jong Min Kim, Jae- Young Choi, and Zhongfan Liu. “Grow Single-Walled Carbon Nanotubes Cross-Bar in One Batch.” J. Phys. Chem. C, 113, 5341, 2009. (Cover Art)

X. Guo

  1. X Guo, A Bernard, DA Orlando, SB Haase, & AJ Hartemink. (2013). “Branching process deconvolution algorithm reveals a detailed cell-cycle transcription program”, Proceedings of the National Academy of Sciences (PNAS), 110, E968-E977.
  2. MB Mayhew, X Guo, SB Haase, & AJ Hartemink. (2012). “Close encounters of the collaborative kind”, IEEE Computer, 45, pp. 24-30. (cover feature)
  3. X Guo, ML Bulyk, & AJ Hartemink. (2012). “Intrinsic disorder within and flanking the DNA-binding domains of human transcription factors”, In Pac Symp Biocomput 2012 (PSB12), pp. 104-115.
  4. X Guo, & AJ Hartemink. (2009). “Domain-oriented edge-based alignment of protein interaction networks”, Bioinformatics, 25, pp. i240-246.

W. Zeng

  1. Biotin-responsive basal ganglia disease maps to 2q36.3 and is due to mutations in SLC19A3. Zeng WQ, Al-Yamani E, Acierno JS Jr, Slaugenhaupt S, Gillis T, MacDonald ME, Ozand PT, Gusella JF. Am J Hum Genet. 2005 Jul;77(1):16-26. Impact Factor 12. 649
  2. Congenital lethal motor neuron disease with a novel defect in ribosome biogenesis. Butterfield RJ1, Stevenson TJ, Xing L, Newcomb TM, Nelson B, Zeng W, Li X, Lu HM, Lu H, Farwell Gonzalez KD, Wei JP, Chao EC, Prior TW, Snyder PJ,Bonkowsky JL, Swoboda KJ. Neurology. 2014 Apr 15;82(15):1322-30. Epub 2014 Mar 19. Impact Factor 8.3
  3. Enhanced utility of family-centered diagnostic exome sequencing with inheritance model-based analysis: results from 500 unselected families with undiagnosed genetic conditions. Farwell KD1, Shahmirzadi L1, El-Khechen D1, Powis Z1, Chao EC2, Davis BT1, Baxter RM1, Zeng W1, Mroske C1, Parra MC1, Gandomi SK1, Lu I1, Li X1, Lu H1, Lu HM1, Salvador D1, Ruble D1, Lao M1, Fischbach S1, Wen J1, Lee S1, Elliott A1, Dunlop CL1, Tang S1. Genetics in Medicine Impact Factor 6.44
  4. ELP2 is a novel gene implicated in neurodevelopmental disabilities. Cohen JS1, Srivastava S, Farwell KD, Lu HM, Zeng W, Lu H, Chao EC, Fatemi A. Am J Med Genet A. 2015 Apr 2.
  5. Diagnostic Exome Sequencing and Tailored Bioinformatics of the Parents of a Deceased Child with Cobalamin Deficiency Suggests Digenic Inheritance of the MTR and LMBRD1 Genes Farwell Gonzalez KD1, Li X, Lu HM, Lu H, Pellegrino JE, Miller RT, Zeng W, Chao EC. JIMD Rep. 2015;15:29-37. Epub 2014 Mar 25.
  6. Expanding the clinical and mutational spectrum of Kaufman oculocerebrofacial syndrome with biallelic UBE3B mutations. Basel-Vanagaite L1, Yilmaz R, Tang S, Reuter MS, Rahner N, Grange DK, Mortenson M, Koty P, Feenstra H, Farwell Gonzalez KD, Sticht H, Boddaert N,Désir J, Anyane-Yeboa K, Zweier C, Reis A, Kubisch C, Jewett T, Zeng W, Borck G. Hum Genet. 2014 Jul;133(7):939-49. Epub 2014 Mar 11.
  7. Xiang, B Xu, F., Zeng WQ, Dan Zi, Ma DQ, Navigating Web-Based Resources for Genetic Testing of Chromosome Abnormalities, CNVs and Gene Mutations. N A J Med Sci. 2014;7(4):163-170. DOI: 10.7156/najms. 2014.0704163
  8. Diagnostic Exome Sequencing Identifies Two Novel IQSEC2 Mutations Associated with X-Linked Intellectual Disability with Seizures: Implications for Genetic Counseling and Clinical Diagnosis. Gandomi SK, Farwell Gonzalez KD, Parra M, Shahmirzadi L, Mancuso J, Pichurin P, Temme R, Dugan S, Zeng W, Tang S. J Genet Couns. 2013.
  9. A human de novo mutation in MYH10 phenocopies the loss of function mutation in mice Rare Diseases 1. Tuzovic L, Yu L, Zeng W, Li X, Lu H, Lu HM, Gonzalez K, Chung WK. Rare Dis. 2013 Aug 14;1:e26144.
  10. Clinical exome sequencing leads to the diagnosis of mitochondrial complex I deficiency in a family with global developmental delays, ataxia, and cerebellar and pons hypoplasia Virginia Kimonis, Kelly Gonzalez, Wenqi Zeng, Phillip Gray, Sha Tang, Jennifer Wei, X. Li, HM. Lu, H. M. Lu, Elizabeth Chao Mitochondrion 11/2013; 13(6):942
  11. Zeng WQ, Gao H, Brueton L, Hutchin T, Gray G, Chakrapani A, Olpin S, Shih VE. Fumarase deficiency caused by homozygous P131R mutation and paternal partial isodisomy of chromosome 1. Am J Med Genet A. 2006; 140(9):1004-9. IF 2.44.
  12. Zeng W, Gillis T, Hakky M, Djoussé L, Myers RH, MacDonald ME, Gusella JF. Genetic analysis of the GRIK2 modifier effect in Huntington's disease. BMC Neurosci. 2006; 7;7:62 IF 2.987.
  13. Yan J, Noltner K, Feng J, Li W, Schroer R, Skinner C, Zeng W, Schwartz CE, Sommer SS. Neurexin 1alpha structural variants associated with autism. Neurosci Lett. 2008; 438(3):368-70. Epub 2008 Apr 25 IF 2.085.
  14. Zhao J, Chen Y, Zeng W et. Al. Pharmacokinetic and pharmacodynamics study of new antidepressant drug: Moclobemide Chinese Journal of Nervous and Mental Diseases. 中国神经精神疾病杂志, 1998; 24(8) 22-28.
  15. Zeng W, Zhao J. A new MAOI antidepressant drug: Moclobemide. International Journal of Psychiatry 国际精神病学杂志, 1995; 22 (1): 8-11.
  16. Zhang Y, Zeng W. A compared study of the copying style of different people that suffered from the different stress. 中国临床心理学杂志, 1994; 1(1): 6-10.
  17. Zeng W The Social Culture Explanation for Symptoms of Mental Disorders. Medicine and Philosophy医学与哲学,1994;15(11):5-8.